Anastrozole refers to anti-estrogen drugs and is synthesized specifically for the treatment of the most common problem among women today – breast cancer. This was the first medicine that got into the class of aromatase inhibitors of the 3rd generation. This medication is able to reversibly bind aromatase by a path of competitive inhibition; the drug inhibits the conversion of androgens to estrogens that are located in the peripheral tissues. The price of Anastrozole can have a significant effect on the level of estrogen in the body. For example, the use of only 1 mg per day can cause a process in which estrogen will be suppressed in 80% of patients and more. Taking into account the powerful effect of the drug at the hormonal level, it is mainly prescribed to women only during postmenopause.
Anastrozole is not associated with androgenic and estrogenic activity. If it is used in the recommended dose for therapy, the drug will not affect the process of producing cortisol and aldosterone.
Anastrozole for men in bodybuilding – the goals to achieve with the intake
Anastrozole for men may interest athletes who use steroids. Previously, before it was invented, athletes were fighting against estrogen with Nolvadex and Proviron. With a combined course, the drugs resulted in good effects on the athletes’ bodies. Unlike the other drugs, however, a solo course of Anastrozole bodybuilding has a much greater effect and therefore becomes very popular. The use of this one and sometimes even ½ tablets of this treatment offer amazing results. During the use of highly aromatized drugs, side effects like gynecomastia may be minimized, the occurrence of which is associated with the use of the ligaments of highly aromatizing agents, agents capable of converting to dihydrotestosterone. In addition, this agent helps to significantly improve the muscles because the excess water goes away.
The long-term use of any drug may cause problems with aromatase inhibitors. Buy Anastrozole online and see; it is able to reduce the side effects of estrogenic nature, but at the same time it is able to block useful properties of estrogen, for example, the suppression of “good” cholesterol.
Anastrozole – all the rules of proper medication reception for amazing results
As a rule, bodybuilders of all stripes start taking Anastrozole’s best therapy replacement, only when there are signs of gynecomastia, or if gynecomastia has already appeared.
The most optimal option to pass the test is to check the level of estrogen. After 10 days – and if you use “short preparations” – testosterone propionate, methane, or 3-4 weeks of drugs with long periods of life are used.
If signs of gynecomastia have not yet appeared, half a tablet or 0.5 mg should be taken every other day; this will be sufficient for the moderate suppression of aromatization and prevention of side effects. After another 10-14 days, it is advisable to reanalyze the test for estradiol and, if necessary, adjust the dosage of the drug more or less.
Anastrozole tablets can be taken at any time, regardless of food intake. However, the most optimal is taking the drug 30 minutes before eating. In this case, the active substance quickly enters the blood.
For prophylactic purposes, this drug should be taken 0.5 mg every day. If you have developed gynecomastia, you should take 1 mg dosage every day. After the disappearance of the signs of gynecomastia, you should continue taking the agent in preventive dosages.
The side effects of Anastrozole tablets that will possibly occur during intake
In general, the Anastrozole side effects associated with taking aromatase inhibitors include hot flashes, soreness of joints, general weakness, rapid fatigue, sudden mood swings, depression, increased blood pressure, swelling of the hands and feet, and headaches. It is also possible to reduce the level of bone mineral density, resulting in the development of osteoporosis and an increased risk of fractures. Sometimes there may be problems in the GI tract, as well as nausea and vomiting. This drug is strictly forbidden to use during pregnancy. It is possible that this treatment will disrupt the development of the fetus. The usage of drugs type by males for a long time can lead to the development of cardiovascular diseases because the drug contains the positive effects of estrogen in terms of cholesterol. Throughout the course of the research, it was found that if you combine steroids that tend to aromatize together with an aromatase inhibitor, there is an obvious suppression of high-density lipoproteins, otherwise known as “good” cholesterol.
Some individual precautions for Anastrozole medicament reception
There is no data on the use of the drug for patients with moderate or severe hepatic impairment or severe renal failure.
In the case of persisting uterine bleeding during Anastrozole intake, consultation and supervision of you gynecologist are necessary.
Estrogen-containing drugs should not be taken simultaneously.
Reduction to the level of circulating estradiol can cause liquefaction of bone mineral density with a subsequent increase in the risk of fracture, and patients with such a high risk should be treated according to guidelines for the therapy of these complications.
There is no evidence of the simultaneous use of this drug and analog preparation of the luteinizing hormone-releasing hormone. It is not known whether this drug improves the results of treatment combined with chemotherapy. Information on safety during long-term treatment with the drug is not available as well.
The efficacy and safety of Anastrozole for sale and Tamoxifen in their simultaneous application, regardless of the status of the hormonal receptors, are comparable to those of single Tamoxifen intake. The exact mechanism of this phenomenon is not known yet.
It is reasonable to be careful during driving and working with potentially dangerous mechanisms since Anastrozole can cause asthenia and drowsiness.